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The Branched Nature of the Nonsense-Mediated mRNA Decay Pathway

Nonsense-mediated mRNA decay (NMD) is a conserved translation-coupled quality control mechanism in all eukaryotes that regulates the expression of a significant fraction of both the aberrant and normal transcriptomes. In vertebrates, NMD has become an essential process owing to expansion of the dive...

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Publicat a:Trends Genet
Autors principals: Yi, Zhongxia, Sanjeev, Manu, Singh, Guramrit
Format: Artigo
Idioma:Inglês
Publicat: 2020
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7854845/
https://ncbi.nlm.nih.gov/pubmed/33008628
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tig.2020.08.010
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