Azithromycin and ciprofloxacin inhibit IL-8 secretion without disrupting human sinonasal epithelial integrity in vitro

BACKGROUND: We recently developed a ciprofloxacin and azithromycin sinus stent (CASS) to target recalcitrant infections in chronic rhinosinusitis (CRS). The objective of this study is to evaluate the anti-inflammatory activity of azithromycin released from the CASS and assess the impact on the integ...

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Pubblicato in:Int Forum Allergy Rhinol
Autori principali: Lim, Dong-Jin, Thompson, Harrison M., Walz, Christopher R., Ayinala, Samrath, Skinner, Daniel, Zhang, Shaoyan, Grayson, Jessica W., Cho, Do-Yeon, Woodworth, Bradford A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2020
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7854841/
https://ncbi.nlm.nih.gov/pubmed/32725797
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/alr.22656
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