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Maternal Immune Activation in Mice Disrupts Proteostasis in the Fetal Brain

Maternal infection and inflammation during pregnancy are associated with neurodevelopmental disorders in offspring, but little is understood about the molecular mechanisms underlying this epidemiologic phenomenon. We leveraged single-cell RNA sequencing to profile transcriptional changes in the mous...

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Detalhes bibliográficos
Publicado no:Nat Neurosci
Main Authors: Kalish, Brian T., Kim, Eunha, Finander, Benjamin, Duffy, Erin E., Kim, Hyunju, Gilman, Casey K., Yim, Yeong Shin, Tong, Lilin, Kaufman, Randal J., Griffith, Eric C., Choi, Gloria B., Greenberg, Michael E., Huh, Jun R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7854524/
https://ncbi.nlm.nih.gov/pubmed/33361822
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41593-020-00762-9
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