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Alcohol induces mitochondrial derangements in alveolar macrophages by upregulating NADPH oxidase 4

Excessive alcohol users have increased risk of developing respiratory infections in part due to oxidative stress-induced alveolar macrophage (AM) phagocytic dysfunction. Chronic ethanol exposure increases cellular oxidative stress in AM via upregulation of NADPH oxidase (Nox) 4, and treatment with t...

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Publicat a:Alcohol
Autors principals: Morris, Niya L., Harris, Frank L., Brown, Lou Ann S., Yeligar, Samantha M.
Format: Artigo
Idioma:Inglês
Publicat: 2020
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7854504/
https://ncbi.nlm.nih.gov/pubmed/33278514
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.alcohol.2020.11.004
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