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MET exon 14-altered lung cancers and MET inhibitor resistance

PURPOSE: MET tyrosine kinase inhibitors (TKIs) can achieve modest clinical outcomes in MET exon 14-altered lung cancers, likely secondary to primary resistance. Mechanisms of primary resistance remain poorly characterized and comprehensive proteomic analyses have not previously been performed. EXPER...

詳細記述

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書誌詳細
出版年:Clin Cancer Res
主要な著者: Guo, Robin, Offin, Michael, Brannon, A. Rose, Chang, Jason, Chow, Andrew, Delasos, Lukas, Girshman, Jeffrey, Wilkins, Olivia, McCarthy, Caroline G., Makhnin, Alex, Falcon, Christina, Scott, Kerry, Tian, Yuan, Cecchi, Fabiola, Hembrough, Todd, Alex, Deepu, Shen, Ronglai, Benayed, Ryma, Li, Bob T., Rudin, Charles M., Kris, Mark G., Arcila, Maria E., Rekhtman, Natasha, Paik, Paul, Zehir, Ahmet, Drilon, Alexander
フォーマット: Artigo
言語:Inglês
出版事項: 2020
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC7854494/
https://ncbi.nlm.nih.gov/pubmed/33172896
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-20-2861
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