Hypo-fractionated FLASH-RT: An effective treatment against glioblastoma that significantly reduces neurocognitive side effects in mice

PURPOSE: Recent data has shown that single fraction irradiation delivered to the whole brain in less than tenths of a second using FLASH radiation therapy (RT), does not elicit neurocognitive deficits in mice. This observation has important clinical implications for the management of invasive and tr...

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Publicat a:Clin Cancer Res
Autors principals: Montay-Gruel, Pierre, Acharya, Munjal M., Jorge, Patrik Gonçalves, Petit, Benoit, Petridis, Ioannis G., Fuchs, Philippe, Leavitt, Ron, Petersson, Kristoffer, Gondre, Maude, Ollivier, Jonathan, Moeckli, Raphael, Bochud, François, Bailat, Claude, Bourhis, Jean, Germond, Jean-François, Limoli, Charles L., Vozenin, Marie-Catherine
Format: Artigo
Idioma:Inglês
Publicat: 2020
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7854480/
https://ncbi.nlm.nih.gov/pubmed/33060122
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-20-0894
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