Long-term neurocognitive benefits of FLASH radiotherapy driven by reduced reactive oxygen species

Here, we highlight the potential translational benefits of delivering FLASH radiotherapy using ultra-high dose rates (>100 Gy⋅s(−1)). Compared with conventional dose-rate (CONV; 0.07–0.1 Gy⋅s(−1)) modalities, we showed that FLASH did not cause radiation-induced deficits in learning and memory in...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Montay-Gruel, Pierre, Acharya, Munjal M., Petersson, Kristoffer, Alikhani, Leila, Yakkala, Chakradhar, Allen, Barrett D., Ollivier, Jonathan, Petit, Benoit, Jorge, Patrik Gonçalves, Syage, Amber R., Nguyen, Thuan A., Baddour, Al Anoud D., Lu, Celine, Singh, Paramvir, Moeckli, Raphael, Bochud, François, Germond, Jean-François, Froidevaux, Pascal, Bailat, Claude, Bourhis, Jean, Vozenin, Marie-Catherine, Limoli, Charles L.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2019
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PNAS Plus
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6561167/
https://ncbi.nlm.nih.gov/pubmed/31097580
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1901777116
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