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Long-term neurocognitive benefits of FLASH radiotherapy driven by reduced reactive oxygen species

Here, we highlight the potential translational benefits of delivering FLASH radiotherapy using ultra-high dose rates (>100 Gy⋅s(−1)). Compared with conventional dose-rate (CONV; 0.07–0.1 Gy⋅s(−1)) modalities, we showed that FLASH did not cause radiation-induced deficits in learning and memory in...

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Publicat a:Proc Natl Acad Sci U S A
Autors principals: Montay-Gruel, Pierre, Acharya, Munjal M., Petersson, Kristoffer, Alikhani, Leila, Yakkala, Chakradhar, Allen, Barrett D., Ollivier, Jonathan, Petit, Benoit, Jorge, Patrik Gonçalves, Syage, Amber R., Nguyen, Thuan A., Baddour, Al Anoud D., Lu, Celine, Singh, Paramvir, Moeckli, Raphael, Bochud, François, Germond, Jean-François, Froidevaux, Pascal, Bailat, Claude, Bourhis, Jean, Vozenin, Marie-Catherine, Limoli, Charles L.
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2019
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6561167/
https://ncbi.nlm.nih.gov/pubmed/31097580
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1901777116
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