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Catalysis by protein acetyltransferase Gcn5

Gcn5 serves as the defining member of the Gcn5-related N-acetyltransferase (GNAT) superfamily of proteins that display a common structural fold and catalytic mechanism involving the transfer of the acyl-group, primarily acetyl-, from CoA to an acceptor nucleophile. In the case of Gcn5, the target is...

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Pubblicato in:Biochim Biophys Acta Gene Regul Mech
Autori principali: Albaugh, Brittany N., Denu, John M.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2020
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7854473/
https://ncbi.nlm.nih.gov/pubmed/32841743
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbagrm.2020.194627
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