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Body Composition Changes with Long-term Pegvisomant Therapy of Acromegaly
CONTEXT: In active acromegaly, the lipolytic and insulin antagonistic effects of growth hormone (GH) excess alter adipose tissue (AT) deposition, reduce body fat, and increase insulin resistance. This pattern reverses with surgical therapy. Pegvisomant treats acromegaly by blocking GH receptor (GHR)...
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| Udgivet i: | J Endocr Soc |
|---|---|
| Main Authors: | , , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Oxford University Press
2021
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7853172/ https://ncbi.nlm.nih.gov/pubmed/33553983 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/jendso/bvab004 |
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