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STING agonist-based treatment promotes vascular normalization and tertiary lymphoid structure formation in the therapeutic melanoma microenvironment
BACKGROUND: The degree of immune infiltration in tumors, especially CD8(+) T cells, greatly impacts patient disease course and response to interventional immunotherapy. Enhancement of tumor infiltrating lymphocyte (TIL) is a critical element of efficacious therapy and one that may be achieved via ad...
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| Veröffentlicht in: | J Immunother Cancer |
|---|---|
| Hauptverfasser: | , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
BMJ Publishing Group
2021
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7852948/ https://ncbi.nlm.nih.gov/pubmed/33526609 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/jitc-2020-001906 |
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