Increased expression of glutamine transporter SNAT2/SLC38A2 promotes glutamine dependence and oxidative stress resistance, and is associated with worse prognosis in triple-negative breast cancer

BACKGROUND: Glutamine (Gln) is an abundant nutrient used by cancer cells. Breast cancers cells and particularly triple-receptor negative breast cancer (TNBC) are reported to be dependent on Gln to produce the energy required for survival and proliferation. Despite intense research on the role of the...

Volledige beschrijving

Bewaard in:
Bibliografische gegevens
Gepubliceerd in:Br J Cancer
Hoofdauteurs: Morotti, Matteo, Zois, Christos E., El-Ansari, Rokaya, Craze, Madeleine L., Rakha, Emad A., Fan, Shih-Jung, Valli, Alessandro, Haider, Syed, Goberdhan, Deborah C. I., Green, Andrew R., Harris, Adrian L.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Nature Publishing Group UK 2020
Onderwerpen:
Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7852531/
https://ncbi.nlm.nih.gov/pubmed/33028955
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41416-020-01113-y
Tags: Voeg label toe
Geen labels, Wees de eerste die dit record labelt!

Gelijkaardige items