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Multiscale modeling of twitch contractions in cardiac trabeculae

Understanding the dynamics of a cardiac muscle twitch contraction is complex because it requires a detailed understanding of the kinetic processes of the Ca(2+) transient, thin-filament activation, and the myosin–actin cross-bridge chemomechanical cycle. Each of these steps has been well defined ind...

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Bibliografske podrobnosti
izdano v:J Gen Physiol
Main Authors: Mijailovich, Srboljub M., Prodanovic, Momcilo, Poggesi, Corrado, Geeves, Michael A., Regnier, Michael
Format: Artigo
Jezik:Inglês
Izdano: Rockefeller University Press 2021
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7852458/
https://ncbi.nlm.nih.gov/pubmed/33512405
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1085/jgp.202012604
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