Shikonin promotes ubiquitination and degradation of cIAP1/2-mediated apoptosis and necrosis in triple negative breast cancer cells

BACKGROUND: Shikonin (SKO) is a natural naphthoquinone derived from Chinese herbal medicine Arnebiae Radix with high development potentials due to its anti-inflammatory and anti-tumor activities. Overwhelming evidences have indicated that SKO can induce both necrosis and apoptosis in cancer cells, w...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Chin Med
Egile Nagusiak: Wang, Anqi, Liu, Jiayu, Yang, Yuhan, Chen, Zhejie, Gao, Caifang, Wang, Zhanguo, Fu, Chaomei, Zou, Liang, Wang, Shengpeng
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: BioMed Central 2021
Gaiak:
Research
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC7851907/
https://ncbi.nlm.nih.gov/pubmed/33526051
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13020-021-00426-1
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