Src kinases relax adherens junctions between the neighbors of apoptotic cells to permit apical extrusion

Epithelia can eliminate apoptotic cells by apical extrusion. This is a complex morphogenetic event where expulsion of the apoptotic cell is accompanied by rearrangement of its immediate neighbors to form a rosette. A key mechanism for extrusion is constriction of an actomyosin network that neighbor...

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Udgivet i:Mol Biol Cell
Main Authors: Teo, Jessica L., Tomatis, Vanesa M., Coburn, Luke, Lagendijk, Anne K., Schouwenaar, Irin-Maya, Budnar, Srikanth, Hall, Thomas E., Verma, Suzie, McLachlan, Robert W., Hogan, Benjamin M., Parton, Robert G., Yap, Alpha S., Gomez, Guillermo A.
Format: Artigo
Sprog:Inglês
Udgivet: The American Society for Cell Biology 2020
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Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7851871/
https://ncbi.nlm.nih.gov/pubmed/32903148
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E20-01-0084
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