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Identification of Candidate Parkinson Disease Genes by Integrating Genome-Wide Association Study, Expression, and Epigenetic Data Sets

IMPORTANCE: Substantial genome-wide association study (GWAS) work in Parkinson disease (PD) has led to the discovery of an increasing number of loci shown reliably to be associated with increased risk of disease. Improved understanding of the underlying genes and mechanisms at these loci will be key...

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發表在:JAMA Neurol
Main Authors: Kia, Demis A., Zhang, David, Guelfi, Sebastian, Manzoni, Claudia, Hubbard, Leon, Reynolds, Regina H., Botía, Juan, Ryten, Mina, Ferrari, Raffaele, Lewis, Patrick A., Williams, Nigel, Trabzuni, Daniah, Hardy, John, Wood, Nicholas W.
格式: Artigo
語言:Inglês
出版: American Medical Association 2021
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC7851759/
https://ncbi.nlm.nih.gov/pubmed/33523105
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1001/jamaneurol.2020.5257
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