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Moving beyond neurons: the role of cell type-specific gene regulation in Parkinson’s disease heritability

Parkinson’s disease (PD), with its characteristic loss of nigrostriatal dopaminergic neurons and deposition of α-synuclein in neurons, is often considered a neuronal disorder. However, in recent years substantial evidence has emerged to implicate glial cell types, such as astrocytes and microglia. I...

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Detalhes bibliográficos
Publicado no:NPJ Parkinsons Dis
Main Authors: Reynolds, Regina H., Botía, Juan, Nalls, Mike A., Hardy, John, Gagliano Taliun, Sarah A., Ryten, Mina
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6470136/
https://ncbi.nlm.nih.gov/pubmed/31016231
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41531-019-0076-6
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