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Moving beyond neurons: the role of cell type-specific gene regulation in Parkinson’s disease heritability

Parkinson’s disease (PD), with its characteristic loss of nigrostriatal dopaminergic neurons and deposition of α-synuclein in neurons, is often considered a neuronal disorder. However, in recent years substantial evidence has emerged to implicate glial cell types, such as astrocytes and microglia. I...

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Bibliografiska uppgifter
I publikationen:NPJ Parkinsons Dis
Huvudupphovsmän: Reynolds, Regina H., Botía, Juan, Nalls, Mike A., Hardy, John, Gagliano Taliun, Sarah A., Ryten, Mina
Materialtyp: Artigo
Språk:Inglês
Publicerad: Nature Publishing Group UK 2019
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC6470136/
https://ncbi.nlm.nih.gov/pubmed/31016231
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41531-019-0076-6
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