FOLFIRI plus cetuximab or bevacizumab for advanced colorectal cancer: final survival and per-protocol analysis of FIRE-3, a randomised clinical trial

BACKGROUND: Cetuximab plus FOLFIRI improved overall survival compared with bevacizumab plus FOLFIRI in KRAS wild-type metastatic colorectal cancer (mCRC) in FIRE-3, but no corresponding benefit was found for progression-free survival. This analysis aimed to determine whether cetuximab improves respo...

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I publikationen:Br J Cancer
Huvudupphovsmän: Heinemann, Volker, von Weikersthal, Ludwig Fischer, Decker, Thomas, Kiani, Alexander, Kaiser, Florian, Al-Batran, Salah-Edin, Heintges, Tobias, Lerchenmüller, Christoph, Kahl, Christoph, Seipelt, Gernot, Kullmann, Frank, Moehler, Markus, Scheithauer, Werner, Held, Swantje, Miller-Phillips, Lisa, Modest, Dominik Paul, Jung, Andreas, Kirchner, Thomas, Stintzing, Sebastian
Materialtyp: Artigo
Språk:Inglês
Publicerad: Nature Publishing Group UK 2020
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Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC7851157/
https://ncbi.nlm.nih.gov/pubmed/33154570
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41416-020-01140-9
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