Peripherally Acting μ-Opioid Receptor Antagonists in the Management of Postoperative Ileus: a Clinical Review

Postoperative ileus (POI) and constipation are common secondary effects of opioids and carry significant clinical and economic impacts. μ-Opioid receptors mediate opioid analgesia in the central nervous system (CNS) and gastrointestinal-related effects in the periphery. Peripherally acting μ-opioid...

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Vydáno v:J Gastrointest Surg
Hlavní autoři: Chamie, Karim, Golla, Vishnukamal, Lenis, Andrew T., Lec, Patrick M., Rahman, Siamak, Viscusi, Eugene R.
Médium: Artigo
Jazyk:Inglês
Vydáno: Springer US 2020
Témata:
Review Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7851096/
https://ncbi.nlm.nih.gov/pubmed/32779081
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11605-020-04671-x
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