Alvimopan, a Novel, Peripherally Acting μ Opioid Antagonist: Results of a Multicenter, Randomized, Double-Blind, Placebo-Controlled, Phase III Trial of Major Abdominal Surgery and Postoperative Ileus

OBJECTIVE: To demonstrate that alvimopan (6 or 12 mg) accelerates recovery of gastrointestinal (GI) function in patients undergoing laparotomy for bowel resection or radical hysterectomy. SUMMARY BACKGROUND DATA: Postoperative ileus (POI) following laparotomy may increase morbidity and extend hospit...

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Detalhes bibliográficos
Main Authors: Wolff, Bruce G., Michelassi, Fabrizio, Gerkin, Todd M., Techner, Lee, Gabriel, Kathie, Du, Wei, Wallin, Bruce A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2004
Assuntos:
Original Articles and Discussions
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1356474/
https://ncbi.nlm.nih.gov/pubmed/15383800
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/01.sla.0000141158.27977.66
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