A lysine ring in HIV capsid pores coordinates IP6 to drive mature capsid assembly

The HIV capsid self-assembles a protective conical shell that simultaneously prevents host sensing whilst permitting the import of nucleotides to drive DNA synthesis. This is accomplished through the construction of dynamic, highly charged pores at the centre of each capsid multimer. The clustering...

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Publicat a:PLoS Pathog
Autors principals: Renner, Nadine, Mallery, Donna L., Faysal, K. M. Rifat, Peng, Wang, Jacques, David A., Böcking, Till, James, Leo C.
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2021
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7850482/
https://ncbi.nlm.nih.gov/pubmed/33524070
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1009164
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