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Inefficiencies in phase II to phase III transition impeding successful drug development in glioblastoma
BACKGROUND: Improving outcomes of patients with glioblastoma (GBM) represents a significant challenge in neuro-oncology. We undertook a systematic review of key parameters of phase II and III trials in GBM to identify and quantify the impact of trial design on this phenomenon. METHODS: Studies betwe...
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| Publicado en: | Neurooncol Adv |
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| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Oxford University Press
2020
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7850118/ https://ncbi.nlm.nih.gov/pubmed/33543145 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/noajnl/vdaa171 |
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