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Piezo1 channels mediate trabecular meshwork mechanotransduction and promote aqueous fluid outflow

Chronic elevations in intraocular pressure (IOP) can cause blindness by compromising the function of trabecular meshwork (TM) cells in the anterior eye but how these cells sense and transduce pressure stimuli is poorly understood. Here, we demonstrate functional expression of two mechanically activa...

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Bibliografiske detaljer
Udgivet i:J Physiol
Main Authors: Yarishkin, Oleg, Phuong, Tam T. T., Baumann, Jackson M., De Ieso, Michael L., Vazquez-Chona, Felix, Rudzitis, Christopher N., Sundberg, Chad, Lakk, Monika, Stamer, W. Daniel, Križaj, David
Format: Artigo
Sprog:Inglês
Udgivet: 2020
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7849624/
https://ncbi.nlm.nih.gov/pubmed/33226641
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/JP281011
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