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Piezo1 channels mediate trabecular meshwork mechanotransduction and promote aqueous fluid outflow

Chronic elevations in intraocular pressure (IOP) can cause blindness by compromising the function of trabecular meshwork (TM) cells in the anterior eye but how these cells sense and transduce pressure stimuli is poorly understood. Here, we demonstrate functional expression of two mechanically activa...

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Bibliografski detalji
Izdano u:J Physiol
Glavni autori: Yarishkin, Oleg, Phuong, Tam T. T., Baumann, Jackson M., De Ieso, Michael L., Vazquez-Chona, Felix, Rudzitis, Christopher N., Sundberg, Chad, Lakk, Monika, Stamer, W. Daniel, Križaj, David
Format: Artigo
Jezik:Inglês
Izdano: 2020
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7849624/
https://ncbi.nlm.nih.gov/pubmed/33226641
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/JP281011
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