TSA-seq reveals a largely conserved genome organization relative to nuclear speckles with small position changes tightly correlated with gene expression changes

TSA-seq mapping suggests that gene distance to nuclear speckles is more deterministic and predictive of gene expression levels than gene radial positioning. Gene expression correlates inversely with distance to nuclear speckles, with chromosome regions of unusually high expression located at the ape...

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Detalhes bibliográficos
Publicado no:Genome Res
Main Authors: Zhang, Liguo, Zhang, Yang, Chen, Yu, Gholamalamdari, Omid, Wang, Yuchuan, Ma, Jian, Belmont, Andrew S.
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2021
Assuntos:
Method
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7849416/
https://ncbi.nlm.nih.gov/pubmed/33355299
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.266239.120
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