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Polygenic Mendelian Randomization
Many exposures considered in Mendelian randomization (MR) studies are polygenic in that they are influenced by thousands of genetic variants. By using many single-nucleotide polymorphisms (SNPs) as instrumental variables, more variation in the exposure is explained, increasing the precision of MR. F...
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| Vydáno v: | Cold Spring Harb Perspect Med |
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| Hlavní autor: | |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
Cold Spring Harbor Laboratory Press
2021
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7849343/ https://ncbi.nlm.nih.gov/pubmed/32229610 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/cshperspect.a039586 |
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