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Pretomanid Pharmacokinetics in the Presence of Rifamycins: Interim Results from a Randomized Trial among Patients with Tuberculosis

Shorter, more potent regimens are needed for tuberculosis. The nitroimidazole pretomanid was recently approved for extensively drug-resistant tuberculosis in combination with bedaquiline and linezolid. Pretomanid may also have benefit as a treatment-shortening agent for drug-sensitive tuberculosis....

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Detalhes bibliográficos
Publicado no:Antimicrob Agents Chemother
Main Authors: Ignatius, Elisa H., Abdelwahab, Mahmoud Tareq, Hendricks, Bronwyn, Gupte, Nikhil, Narunsky, Kim, Wiesner, Lubbe, Barnes, Grace, Dawson, Rodney, Dooley, Kelly E., Denti, Paolo
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7849006/
https://ncbi.nlm.nih.gov/pubmed/33229425
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01196-20
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