Atypical Mutation in Neisseria gonorrhoeae 23S rRNA Associated with High-Level Azithromycin Resistance

A2059G mutation in the 23S rRNA gene is the only reported mechanism conferring high-level azithromycin resistance (HL-AZMR) in Neisseria gonorrhoeae. Through U.S. gonococcal antimicrobial resistance surveillance projects, we identified four HL-AZMR gonococcal isolates lacking this mutational genotyp...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Antimicrob Agents Chemother
Egile Nagusiak: Pham, Cau D., Nash, Evelyn, Liu, Hsi, Schmerer, Matthew W., Sharpe, Samera, Woods, Grace, Roland, Brad, Schlanger, Karen, St. Cyr, Sancta B., Carlson, Jonathan, Sellers, Kevin, Olsen, Aaron, Sanon, Ruth, Hardin, Henrietta, Soge, Olusegun O., Raphael, Brian H., Kersh, Ellen N.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society for Microbiology 2021
Gaiak:
Mechanisms of Resistance
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC7848993/
https://ncbi.nlm.nih.gov/pubmed/33139288
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00885-20
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