Atypical Mutation in Neisseria gonorrhoeae 23S rRNA Associated with High-Level Azithromycin Resistance

A2059G mutation in the 23S rRNA gene is the only reported mechanism conferring high-level azithromycin resistance (HL-AZMR) in Neisseria gonorrhoeae. Through U.S. gonococcal antimicrobial resistance surveillance projects, we identified four HL-AZMR gonococcal isolates lacking this mutational genotyp...

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Detalhes bibliográficos
Publicado no:Antimicrob Agents Chemother
Main Authors: Pham, Cau D., Nash, Evelyn, Liu, Hsi, Schmerer, Matthew W., Sharpe, Samera, Woods, Grace, Roland, Brad, Schlanger, Karen, St. Cyr, Sancta B., Carlson, Jonathan, Sellers, Kevin, Olsen, Aaron, Sanon, Ruth, Hardin, Henrietta, Soge, Olusegun O., Raphael, Brian H., Kersh, Ellen N.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2021
Assuntos:
Mechanisms of Resistance
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7848993/
https://ncbi.nlm.nih.gov/pubmed/33139288
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00885-20
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