Atypical Mutation in Neisseria gonorrhoeae 23S rRNA Associated with High-Level Azithromycin Resistance

A2059G mutation in the 23S rRNA gene is the only reported mechanism conferring high-level azithromycin resistance (HL-AZMR) in Neisseria gonorrhoeae. Through U.S. gonococcal antimicrobial resistance surveillance projects, we identified four HL-AZMR gonococcal isolates lacking this mutational genotyp...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Antimicrob Agents Chemother
Prif Awduron: Pham, Cau D., Nash, Evelyn, Liu, Hsi, Schmerer, Matthew W., Sharpe, Samera, Woods, Grace, Roland, Brad, Schlanger, Karen, St. Cyr, Sancta B., Carlson, Jonathan, Sellers, Kevin, Olsen, Aaron, Sanon, Ruth, Hardin, Henrietta, Soge, Olusegun O., Raphael, Brian H., Kersh, Ellen N.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Society for Microbiology 2021
Pynciau:
Mechanisms of Resistance
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC7848993/
https://ncbi.nlm.nih.gov/pubmed/33139288
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00885-20
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