Atypical Mutation in Neisseria gonorrhoeae 23S rRNA Associated with High-Level Azithromycin Resistance

A2059G mutation in the 23S rRNA gene is the only reported mechanism conferring high-level azithromycin resistance (HL-AZMR) in Neisseria gonorrhoeae. Through U.S. gonococcal antimicrobial resistance surveillance projects, we identified four HL-AZMR gonococcal isolates lacking this mutational genotyp...

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Bibliografische gegevens
Gepubliceerd in:Antimicrob Agents Chemother
Hoofdauteurs: Pham, Cau D., Nash, Evelyn, Liu, Hsi, Schmerer, Matthew W., Sharpe, Samera, Woods, Grace, Roland, Brad, Schlanger, Karen, St. Cyr, Sancta B., Carlson, Jonathan, Sellers, Kevin, Olsen, Aaron, Sanon, Ruth, Hardin, Henrietta, Soge, Olusegun O., Raphael, Brian H., Kersh, Ellen N.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society for Microbiology 2021
Onderwerpen:
Mechanisms of Resistance
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7848993/
https://ncbi.nlm.nih.gov/pubmed/33139288
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00885-20
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