Silencing Artemis Enhances Colorectal Cancer Cell Sensitivity to DNA-Damaging Agents

Artemis is a key protein of NHEJ (nonhomologous end joining), which is the major pathway for the repair of IR-induced DSBs in mammalian cells. However, the expression of Artemis in tumors and the influence of silencing Artemis on tumor sensitivity to radiation have not been investigated fully. In th...

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Vydáno v:Oncol Res
Hlavní autoři: Liu, Hai, Wang, Xuanxuan, Huang, Aihua, Gao, Huaping, Sun, Yikan, Jiang, Tingting, Shi, Liming, Wu, Xianjie, Dong, Qinghua, Sun, Xiaonan
Médium: Artigo
Jazyk:Inglês
Vydáno: Cognizant Communication Corporation 2018
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7848410/
https://ncbi.nlm.nih.gov/pubmed/29426373
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3727/096504018X15179694020751
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