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Treatment with therapeutic anticoagulation is not associated with immunotherapy response in advanced cancer patients

BACKGROUND: Recent preclinical data suggest that there may be therapeutic synergy between immune checkpoint blockade and inhibition of the coagulation cascade. Here, we investigate whether patients who received immune checkpoint inhibitors (ICI) and were on concomitant anticoagulation (AC) experienc...

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Détails bibliographiques
Publié dans:J Transl Med
Auteurs principaux: Johannet, Paul, Sawyers, Amelia, Gulati, Nicholas, Donnelly, Douglas, Kozloff, Samuel, Qian, Yingzhi, Floristan, Alfredo, Hernando, Eva, Zhong, Judy, Osman, Iman
Format: Artigo
Langue:Inglês
Publié: BioMed Central 2021
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7847556/
https://ncbi.nlm.nih.gov/pubmed/33516263
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12967-021-02712-w
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