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Seizure-induced activation of the HPA axis increases seizure frequency and comorbid depression-like behaviors

Our laboratory recently demonstrated that seizures activate the hypothalamic-piuitary-adrenal (HPA) axis, increasing circulating levels of corticosterone [1]. Given the well-established proconvulsant actions of corticosterone, we hypothesized that seizure-induced activation of the HPA axis may contr...

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Detalhes bibliográficos
Publicado no:Epilepsy Behav
Main Authors: Hooper, Andrew, Paracha, Rumzah, Maguire, Jamie
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7847314/
https://ncbi.nlm.nih.gov/pubmed/29186699
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.yebeh.2017.10.025
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