The Roles of Comorbidity and Trauma Exposure and Its Timing in Shaping HPA Axis Patterns in Depression

BACKGROUND: Much work has documented hypothalamic pituitary adrenal (HPA) axis abnormalities in major depressive disorder (MDD), but inconsistencies leave this system’s role in the illness unclear. Comparisons across studies are complicated by variation in co-morbidity (Posttraumatic Stress Disorder...

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Pubblicato in:Psychoneuroendocrinology
Autori principali: Mayer, Stefanie E., Peckins, Melissa, Kuhlman, Kate R., Rajaram, Nirmala, Lopez-Duran, Nestor L., Young, Elizabeth A., Abelson, James L.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2020
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7502500/
https://ncbi.nlm.nih.gov/pubmed/32593866
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.psyneuen.2020.104776
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