Childhood trauma, HPA axis activity and antidepressant response in patients with depression

Childhood trauma is among the most potent contributing risk factors for depression and is associated with poor treatment response. Hypothalamic-pituitary-adrenal (HPA) axis abnormalities have been linked to both childhood trauma and depression, but the underlying mechanisms are poorly understood. Th...

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Publicado en:Brain Behav Immun
Main Authors: Nikkheslat, Naghmeh, McLaughlin, Anna P., Hastings, Caitlin, Zajkowska, Zuzanna, Nettis, Maria A., Mariani, Nicole, Enache, Daniela, Lombardo, Giulia, Pointon, Linda, Cowen, Philip J., Cavanagh, Jonathan, Harrison, Neil A., Bullmore, Edward T., Pariante, Carmine M., Mondelli, Valeria
Formato: Artigo
Idioma:Inglês
Publicado: Elsevier 2020
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7327513/
https://ncbi.nlm.nih.gov/pubmed/31794798
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbi.2019.11.024
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