Whole-blood expression of inflammasome- and glucocorticoid-related mRNAs correctly separates treatment-resistant depressed patients from drug-free and responsive patients in the BIODEP study

The mRNA expression signatures associated with the ‘pro-inflammatory’ phenotype of depression, and the differential signatures associated with depression subtypes and the effects of antidepressants, are still unknown. We examined 130 depressed patients (58 treatment-resistant, 36 antidepressant-resp...

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Publicado no:Transl Psychiatry
Main Authors: Cattaneo, Annamaria, Ferrari, Clarissa, Turner, Lorinda, Mariani, Nicole, Enache, Daniela, Hastings, Caitlin, Kose, Melisa, Lombardo, Giulia, McLaughlin, Anna P., Nettis, Maria A., Nikkheslat, Naghmeh, Sforzini, Luca, Worrell, Courtney, Zajkowska, Zuzanna, Cattane, Nadia, Lopizzo, Nicola, Mazzelli, Monica, Pointon, Linda, Cowen, Philip J., Cavanagh, Jonathan, Harrison, Neil A., de Boer, Peter, Jones, Declan, Drevets, Wayne C., Mondelli, Valeria, Bullmore, Edward T., Pariante, Carmine M.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7376244/
https://ncbi.nlm.nih.gov/pubmed/32699209
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41398-020-00874-7
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