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Planar cell polarity defects and hearing loss in sperm-associated antigen 6 (Spag6)-deficient mice

Spag6 encodes an axoneme central apparatus protein that is required for normal flagellar and cilia motility. Recent findings suggest that Spag6 also plays a role in ciliogenesis, orientation of cilia basal feet, and planar polarity. Sensory cells of the inner ear display unique structural features t...

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Detalhes bibliográficos
Publicado no:Am J Physiol Cell Physiol
Main Authors: Li, Xiaofei, Zhang, Daogong, Xu, Lei, Han, Yuechen, Liu, Wenwen, Li, Wei, Fan, Zhaomin, Costanzo, Richard M., Strauss, III, Jerome F., Zhang, Zhibing, Wang, Haibo
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2021
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7846974/
https://ncbi.nlm.nih.gov/pubmed/33175573
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpcell.00166.2020
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