Sperm-Associated Antigen 6 (SPAG6) Deficiency and Defects in Ciliogenesis and Cilia Function: Polarity, Density, and Beat

SPAG6, an axoneme central apparatus protein, is essential for function of ependymal cell cilia and sperm flagella. A significant number of Spag6-deficient mice die with hydrocephalus, and surviving males are sterile because of sperm motility defects. In further exploring the ciliary dysfunction in S...

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Main Authors: Teves, Maria E., Sears, Patrick R., Li, Wei, Zhang, Zhengang, Tang, Waixing, van Reesema, Lauren, Costanzo, Richard M., Davis, C. William, Knowles, Michael R., Strauss, Jerome F., Zhang, Zhibing
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2014
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4204823/
https://ncbi.nlm.nih.gov/pubmed/25333478
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0107271
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