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Transcriptome from opaque cornea of Fanconi anemia patient uncovers fibrosis and two connected players

Congenital corneal opacities (CCO) are a group of blinding corneal disorders, where the underlying molecular mechanisms are poorly understood. Phenotyping through specialized imaging and histopathology analysis, together with assessment of key transcriptomic changes (including glycosaminoglycan meta...

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Détails bibliographiques
Publié dans:Mol Genet Metab Rep
Auteurs principaux: Chauhan, Bharesh K., Medsinge, Anagha, Scanga, Hannah L., Chu, Charleen T., Nischal, Ken K.
Format: Artigo
Langue:Inglês
Publié: Elsevier 2021
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7846932/
https://ncbi.nlm.nih.gov/pubmed/33552906
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ymgmr.2021.100712
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