A single-dose live attenuated chimeric vaccine candidate against Zika virus

The mosquito-borne Zika virus is an emerging pathogen from the Flavivirus genus for which there are no approved antivirals or vaccines. Using the clinically validated PDK-53 dengue virus vaccine strain as a backbone, we created a chimeric dengue/Zika virus, VacDZ, as a live attenuated vaccine candid...

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Enregistré dans:
Détails bibliographiques
Publié dans:NPJ Vaccines
Auteurs principaux: Chin, Wei-Xin, Lee, Regina Ching Hua, Kaur, Parveen, Lew, Tian Sheng, Yogarajah, Thinesshwary, Kong, Hao Yuin, Teo, Zi-Yun, Salim, Cyrill Kafi, Zhang, Rong-Rong, Li, Xiao-Feng, Alonso, Sylvie, Qin, Cheng-Feng, Chu, Justin Jang Hann
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group UK 2021
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7846741/
https://ncbi.nlm.nih.gov/pubmed/33514743
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41541-021-00282-y
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