Radiation-induced eosinophils improve cytotoxic T lymphocyte recruitment and response to immunotherapy

The efficacy of cancer immunotherapy is dictated by CD8(+) T cell infiltration and the nature of the tumor microenvironment (TME). By inflaming the TME to favor CD8(+) T cell immunity, radiation is now widely considered as a neoadjuvant for immunomodulation. Here, we observed that local irradiation...

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Detalhes bibliográficos
Publicado no:Sci Adv
Main Authors: Cheng, Jia-Nan, Luo, Wen, Sun, Chengdu, Jin, Zheng, Zeng, Xianghua, Alexander, Peter B., Gong, Zhihua, Xia, Xin, Ding, Xiaofang, Xu, Shouxia, Zou, Ping, Wan, Yisong Y., Jia, Qingzhu, Li, Qi-Jing, Zhu, Bo
Formato: Artigo
Idioma:Inglês
Publicado em: American Association for the Advancement of Science 2021
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7846170/
https://ncbi.nlm.nih.gov/pubmed/33514544
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciadv.abc7609
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