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Ciona Brachyury proximal and distal enhancers have different FGF dose-response relationships

Many genes are regulated by two or more enhancers that drive similar expression patterns. Evolutionary theory suggests that these seemingly redundant enhancers must have functionally important differences. In the simple ascidian chordate Ciona, the transcription factor Brachyury is induced exclusive...

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Veröffentlicht in:PLoS Genet
Hauptverfasser: Harder, Matthew J., Hix, Julie, Reeves, Wendy M., Veeman, Michael T.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2021
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7846015/
https://ncbi.nlm.nih.gov/pubmed/33465083
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1009305
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