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Low frequency mitochondrial DNA heteroplasmy SNPs in blood, retina, and [RPE+choroid] of age-related macular degeneration subjects

PURPOSE: Mitochondrial (mt) DNA damage is associated with age-related macular degeneration (AMD) and other human aging diseases. This study was designed to quantify and characterize mtDNA low-frequency heteroplasmy single nucleotide polymorphisms (SNPs) of three different tissues isolated from AMD s...

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Publicado en:PLoS One
Autores principales: Atilano, Shari R., Udar, Nitin, Satalich, Timothy A., Udar, Viraat, Chwa, Marilyn, Kenney, M. Cristina
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2021
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7846006/
https://ncbi.nlm.nih.gov/pubmed/33513185
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0246114
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