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Multiscale modeling shows that dielectric differences make Na(V) channels faster than K(V) channels
The generation of action potentials in excitable cells requires different activation kinetics of voltage-gated Na (Na(V)) and K (K(V)) channels. Na(V) channels activate much faster and allow the initial Na(+) influx that generates the depolarizing phase and propagates the signal. Recent experimental...
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| 發表在: | J Gen Physiol |
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| Main Authors: | , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
Rockefeller University Press
2021
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7845922/ https://ncbi.nlm.nih.gov/pubmed/33502441 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1085/jgp.202012706 |
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