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Simulation of Gating Currents of the Shaker K Channel Using a Brownian Model of the Voltage Sensor

The physical mechanism underlying the voltage-dependent gating of K channels is usually addressed theoretically using molecular dynamics simulations. However, besides being computationally very expensive, this approach is presently unable to fully predict the behavior of fundamental variables of cha...

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Detalhes bibliográficos
Publicado no:Biophys J
Main Authors: Catacuzzeno, Luigi, Franciolini, Fabio
Formato: Artigo
Idioma:Inglês
Publicado em: The Biophysical Society 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7018989/
https://ncbi.nlm.nih.gov/pubmed/31653450
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2019.09.039
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