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Association of Zinc Finger Antiviral Protein Binding to Viral Genomic RNA with Attenuation of Replication of Echovirus 7

Previous studies have implicated both zinc finger antiviral protein (ZAP) and oligoadenylate synthetase 3 (OAS3)/RNase L in the attenuation of RNA viruses with elevated CpG and UpA dinucleotides. Mechanisms and interrelationships between these two pathways were investigated using an echovirus 7 (E7)...

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Veröffentlicht in:mSphere
Hauptverfasser: Goonawardane, Niluka, Nguyen, Dung, Simmonds, Peter
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2021
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7845596/
https://ncbi.nlm.nih.gov/pubmed/33408233
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mSphere.01138-20
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