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Use of a small DNA virus model to investigate mechanisms of CpG dinucleotide-induced attenuation of virus replication

Suppression of the CpG dinucleotide is widespread in RNA viruses infecting vertebrates and plants, and in the genomes of retroviruses and small mammalian DNA viruses. The functional basis for CpG suppression in the latter was investigated through the construction of mutants of the parvovirus, minute...

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Bibliografiske detaljer
Udgivet i:J Gen Virol
Main Authors: Loew, Lisa, Goonawardane, Niluka, Ratcliff, Jeremy, Nguyen, Dung, Simmonds, Peter
Format: Artigo
Sprog:Inglês
Udgivet: Microbiology Society 2020
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7879557/
https://ncbi.nlm.nih.gov/pubmed/32783803
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1099/jgv.0.001477
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