Pioglitazone-Mediated Attenuation of Experimental Colitis Relies on Cleaving of Annexin A1 Released by Macrophages

Ulcerative colitis and Crohn’s disease are chronic inflammatory bowel diseases (IBDs) which burden health systems worldwide; available pharmacological therapies are limited and cost-intensive. Use of peroxisome proliferator activated-receptor γ (PPARγ) ligands for IBD treatment, while promising, lac...

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Detalhes bibliográficos
Publicado no:Front Pharmacol
Main Authors: da Rocha, Gustavo Henrique Oliveira, de Paula-Silva, Marina, Broering, Milena Fronza, Scharf, Pablo Rhasan dos Santos, Matsuyama, Larissa Satiko Alcântara Sekimoto, Maria-Engler, Silvya Stuchi, Farsky, Sandra Helena Poliselli
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2020
Assuntos:
Pharmacology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7845455/
https://ncbi.nlm.nih.gov/pubmed/33519451
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2020.591561
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