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Structural basis of enzyme activity regulation by the propeptide of l-lysine α-oxidase precursor from Trichoderma viride

Harmuful proteins are usually synthesized as inactive precursors and are activated by proteolytic processing. l-Amino acid oxidase (LAAO) is a flavoenzyme that catalyzes the oxidative deamination of l-amino acid to produce a 2-oxo acid with ammonia and highly toxic hydrogen peroxide and, therefore,...

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Bibliographische Detailangaben
Veröffentlicht in:J Struct Biol X
Hauptverfasser: Kitagawa, Masaki, Ito, Nanako, Matsumoto, Yuya, Saito, Masaya, Tamura, Takashi, Kusakabe, Hitoshi, Inagaki, Kenji, Imada, Katsumi
Format: Artigo
Sprache:Inglês
Veröffentlicht: Elsevier 2021
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7844570/
https://ncbi.nlm.nih.gov/pubmed/33554108
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.yjsbx.2021.100044
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