Peptide-Conjugated Phosphorodiamidate Morpholino Oligomers Retain Activity against Multidrug-Resistant Pseudomonas aeruginosa In Vitro and In Vivo

Most antimicrobials currently in the clinical pipeline are modifications of existing classes of antibiotics and are considered short-term solutions due to the emergence of resistance. Pseudomonas aeruginosa represents a major challenge for new antimicrobial drug discovery due to its versatile lifest...

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Bibliografiske detaljer
Udgivet i:mBio
Main Authors: Moustafa, Dina A., Wu, Ashley W., Zamora, Danniel, Daly, Seth M., Sturge, Carolyn R., Pybus, Christine, Geller, Bruce L., Goldberg, Joanna B., Greenberg, David E.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2021
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7844538/
https://ncbi.nlm.nih.gov/pubmed/33436433
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mBio.02411-20
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